Publications

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2005
Baptista, P., G. Doria, A. Matias, L. Osorio, E. Pereira, and F. Ricardo. Direct detection of mutations/SNPs using DNA-derivatised gold nanoparticles In Congress of Clinical Chemistry and Laboratory Medicine. Jena, Germany, 2005.
2007
Silva, LB, P. Baptista, L. Raniero, G. Doria, R. Franco, R. Martins, E. Fortunato, and IEEE. "Novel optoelectronic platform using an amorphous/nanocrystalline silicon biosensor for the specific identification of unamplified nucleic acid sequences based on gold nanoparticle probes." Transducers '07 & Eurosensors Xxi, Digest of Technical Papers, Vols 1 and 2 (2007): U472-U473. Abstract

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Martins, Rodrigo, Pedro Baptista, Leandro Raniero, Gonçalo Doria, Leonardo Silva, Ricardo Franco, and Elvira Fortunato. "Amorphous/nanocrystalline silicon biosensor for the specific identification of unamplified nucleic acid sequences using gold nanoparticle probes." Appl. Phys. Lett. 90 (2007).
2008
Baptista, P., E. Pereira, P. Eaton, G. Doria, A. Miranda, I. Gomes, P. Quaresma, and R. Franco. "Gold nanoparticles for the development of clinical diagnosis methods." Anal Bioanal Chem 391 (2008): 943-50. AbstractWebsite

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Martins, R., P. Baptista, L. Silva, L. Raniero, G. Doria, R. Franco, and E. Fortunato. "Identification of unamplified genomic DNA sequences using gold nanoparticle probes and a novel thin film photodetector." Journal of Non-Crystalline Solids 354 (2008): 2580-2584. Abstract

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Baptista, Pedro, Eulália Pereira, Peter Eaton, Gonçalo Doria, Adelaide Miranda, Inês Gomes, Pedro Quaresma, and Ricardo Franco. "Gold Nanoparticles for the Development of Clinical Diagnosis Methods." Anal Bioanal Chem. 391 (2008): 943-950.
2010
Veigas, B., D. Machado, J. Perdigão, I. Portugal, I. Couto, M. Viveiros, and P. V. Baptista. "Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis." Nanotechnology 21 (2010): 415101. AbstractWebsite

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Bernacka-Wojcik, Iwona, Rohan Senadeera, Pawel Jerzy Wojcik, Leonardo Bione Silva, Gonçalo Doria, Pedro Baptista, Hugo Aguas, Elvira Fortunato, and Rodrigo Martins. "Inkjet printed and "doctor blade" TiO2 photodetectors for DNA biosensors." Biosens. Bioelectron. 25 (2010): 1229-1234.
2011
Silva, LB, B. Veigas, G. Doria, P. Costa, J. Inácio, R. Martins, E. Fortunato, and P. V. Baptista. "Portable optoelectronic biosensing platform for identification of mycobacteria from the Mycobacterium tuberculosis complex." Biosens Bioelectron 26 (2011): 2012-7. AbstractWebsite

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Branquinho, R., B. Veigas, J. V. Pinto, R. Martins, E. Fortunato, and P. V. Baptista. "Real-time monitoring of PCR amplification of proto-oncogene c-MYC using a Ta₂O₅ electrolyte-insulator-semiconductor sensor." Biosens Bioelectron 28 (2011): 44-9. AbstractWebsite

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2012
Conde, Joao, Alfredo Ambrosone, Vanesa Sanz, Yulan Hernandez, Valentina Marchesano, Furong Tian, Hannah Child, Catherine C. Berry, Ricardo M. Ibarra, Pedro V. Baptista, Claudia Tortiglione, and Jesus M. de la Fuente. "Design of Multifunctional Gold Nanoparticles for In Vitro and In Vivo Gene Silencing." Acs Nano 6 (2012): 8316-8324. Abstract

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Guirgis, Bassem S. S., Claudia Sa e Cunha, Ines Gomes, Miguel Cavadas, Isabel Silva, Goncalo Doria, Gregory L. Blatch, Pedro V. Baptista, Eulalia Pereira, Hassan M. E. Azzazy, Maria M. Mota, Miguel Prudencio, and Ricardo Franco. "Gold nanoparticle-based fluorescence immunoassay for malaria antigen detection." Analytical and Bioanalytical Chemistry 402 (2012): 1019-1027. Abstract

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Veigas, Bruno, Jorge M. Jacob, Mafalda N. Costa, David S. Santos, Miguel Viveiros, Joao Inacio, Rodrigo Martins, Pedro Barquinha, Elvira Fortunato, and Pedro Viana Baptista. "Gold on paper-paper platform for Au-nanoprobe TB detection." Lab on a Chip 12 (2012): 4802-4808. Abstract

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Sanz, Vanesa, Joao Conde, Alfredo Ambrosone, Yulan Hernandez, Valentina Marchesasno, Giovani G. Estrada, Manuel R. Ibarra, Pedro V. Baptista, Furong Tian, Claudia Tortiglione, and Jesus M. de la Fuente. "Multifunctional gold nanoparticles for gene silencing." Abstracts of Papers of the American Chemical Society 243 (2012). Abstract

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Machado, Diana, Isabel Couto, João Perdigão, Liliana Rodrigues, Isabel Portugal, Pedro Baptista, Bruno Veigas, Leonard Amaral, and Miguel Viveiros. "Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis." PLoS ONE 7 (2012): e34538.
2013
Conde, J., A. Ambrosone, Y. Hernandez, V. Marchesano, F. Tian, M. Ricardo Ibarra, P. V. Baptista, C. Tortiglione, and J. M. de la Fuente. "Designing gold nanoparticles for in vivo gene silencing as a new therapeutic tool." Human Gene Therapy 24 (2013): A24. Abstract

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Bernacka-Wojcik, Iwona, Paulo Lopes, Ana Catarina Vaz, Bruno Veigas, Pawel Jerzy Wojcik, Pedro Simões, David Barata, Elvira Fortunato, Pedro V. Baptista, Hugo Águas, and Rodrigo Martins. "Bio-microfluidic platform for gold nanoprobe based DNA detection—application to Mycobacterium tuberculosis." Biosens Bioelectron 48 (2013): 87-93. AbstractWebsite

We have projected and fabricated a microfluidic platform for DNA sensing that makes use of an optical colorimetric detection method based on gold nanoparticles. The platform was fabricated using replica moulding technology in PDMS patterned by high-aspect-ratio SU-8 moulds. Biochips of various geometries were tested and evaluated in order to find out the most efficient architecture, and the rational for design, microfabrication and detection performance is presented. The best biochip configuration has been successfully applied to the DNA detection of Mycobacterium tuberculosis using only 3 µl on DNA solution (i.e. 90 ng of target DNA), therefore a 20-fold reduction of reagents volume is obtained when compared with the actual state of the art.

Branquinho, R., J. V. Pinto, T. Busani, P. Barquinha, L. Pereira, P. V. Baptista, R. Martins, and E. Fortunato. "Plastic Compatible Sputtered Ta2O5 Sensitive Layer for Oxide Semiconductor TFT Sensors." J. Display Technol 9 (2013): 723-728.
2014
Reimão-Pinto, M. M., A. Cordeiro, C. Almeida, A. V. Pinheiro, A. Moro, J. C. Lima, and P. V. Baptista. "Dual-color control of nucleotide polymerization sensed by a fluorescence actuator." Photochem Photobiol Sci 13 (2014): 751-6. AbstractWebsite

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Bernacka-Wojcik, Iwona, Susana Ribeiro, Pawel Jerzy Wojcik, Pedro Urbano Alves, Tito Busani, Elvira Fortunato, Pedro Viana Baptista, Jose Antonio Covas, Hugo Aguas, Loic Hilliou, and Rodrigo Martins. "Experimental optimization of a passive planar rhombic micromixer with obstacles for effective mixing in a short channel length." Rsc Advances 4 (2014): 56013-56025. Abstract

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Luis, Daniel V., Joana Silva, Ana Isabel Tomaz, Rodrigo F. M. de Almeida, Miguel Larguinho, Pedro V. Baptista, Luisa M. D. R. S. Martins, Telma F. S. Silva, Pedro M. Borralho, Cecilia M. P. Rodrigues, Antonio S. Rodrigues, Armando J. L. Pombeiro, and Alexandra R. Fernandes. "Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies." Journal of Biological Inorganic Chemistry 19 (2014): 787-803. Abstract

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Veigas, B., R. Branquinho, J. V. Pinto, P. J. Wojcik, R. Martins, E. Fortunato, and P. V. Baptista. "Ion sensing (EIS) real-time quantitative monitorization of isothermal DNA amplification." Biosens Bioelectron 52 (2014): 50-5. AbstractWebsite

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Costa, M. N., B. Veigas, J. M. Jacob, D. S. Santos, J. Gomes, P. V. Baptista, R. Martins, J. Inacio, and E. Fortunato. "A low cost, safe, disposable, rapid and self-sustainable paper-based platform for diagnostic testing: lab-on-paper." Nanotechnology 25 (2014). Abstract

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Bao, Chenchen, Joao Conde, Ester Polo, Pablo del Pino, Maria Moros, Pedro V. Baptista, Valeria Grazu, Daxiang Cui, and Jesus M. de la Fuente. "A promising road with challenges: where are gold nanoparticles in translational research?" Nanomedicine 9 (2014): 2353-2370. Abstract

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Conde, Joao, Jorge T. Dias, Valeria Grazu, Maria Moros, Pedro V. Baptista, and Jesus M. de la Fuente. "Revisiting 30 years of biofunctionalization and surface chemistry of inorganic nanoparticles for nanomedicine." Frontiers in Chemistry 2 (2014). Abstract

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