Recent Publications

Latest research from our team members

GONÇALVES, C. & COSTA, P.M. (2020, in press). Histochemical detection of free thiols in glandular cells and tissues of different marine Polychaeta. Histochemistry and Cell Biology. (doi: 10.1007/s00418-020-01889-3)

D'AMBROSIO, M., SANTOS, A.C., ALEJO-ARMIJO, A., PAROLA, J. & COSTA, P.M. (2020). Light-mediated toxicity of porphyrin-like pigments from a marine polychaeta. Marine Drugs 18, 302. (doi: 10.3390/md18060302)

BEJAOUI, S., MICHÁN, C., TELAHIGUEC, K., NECHIC, S., EL CAFSIQ, M., SOUDANIB, N., BLASCO, J., COSTA, P.M. & ALHAMA, J. (2020). Metal body burden and tissue oxidative status in the bivalve Venerupis decussata. Assessment of environmental quality in transitional waters. Marine Environmental Research 159, 105000. (doi: 10.1016/j.marenvres.2020.105000)

MARTINS, C. & COSTA, P.M. (2020, in press). Technical updates to the Comet assay in vivo for assessing DNA damage in zebrafish embryos from fresh and frozen cell suspensions. Zebrafish 17, 220-228. (doi: 10.1089/zeb.2020.1857)

MARTINS, C. DREIJ, K. & COSTA, P.M. (2019). The state-of-the art of environmental toxicogenomics: Challenges and perspectives of “omics” approaches directed to toxicant mixtures. International Journal of Environmental and Human Health 16, 4718. (doi: 10.3390/ijerph16234718

PEDROSA, P., CORVO, M.L., FERREIRA-SILVA, M., MARTINS, P., COLA CARVALHEIRO, M.C., COSTA, P.M., MARTINS, C., MARTINS, L.M.D.R.S., BAPTISTA, P.V. & FERNANDES, A.R. (2019). Targeting cancer resistance via multifunctional gold-nanoparticles. International Journal of Molecular Sciences 20, 5510. (doi: 10.3390/ijms20215510)

MARTINS, C., RODRIGO, A.P., CABRITA, L., HENRIQUES, P., PAROLA, A.J. & COSTA, P.M. (2019). The complexity of porphyrin-like pigments in a marine annelid sheds new light on haem metabolism in aquatic invertebrates. Scientific Reports 9, 12930. (doi: 10.1038/s41598-019-49433-1)

CUNHA, M.L., MARTINS, C., GROSSO, A.R. & COSTA, P.M. (2019). Mytilus galloprovincialis CYP1A-like mRNAs reveal closer proximity of mytilid CYP1A to the eumetazoan CYP2 Family. Aquatic Toxicology 214, 105260. (doi: 10.1016/j.aquatox.2019.105260)

RODRIGO, A.P., & COSTA, P.M. (2019). The hidden biotechnological potential of marine invertebrates: The Polychaeta case study. Environmental Research 173, 270-280. (doi: 10.1016/j.envres.2019.03.048)

ALVES-BARROCO, C., ROMA-RODRIGUES, C., RAPOSO, L.R., BRÁS, C., DINIZ, M.,  CAÇO; J., COSTA, P.M., SANTOS-SANCHES, I., & FERNANDES, A.R. (2019). Streptococcus dysgalactiae subsp. dysgalactiae isolated from milk of the bovine udder as emerging pathogens: In vitro and in vivo infection of human cells and zebrafish (Danio rerio) as biological models. MicrobiologyOpen  8,(1), e00623 (doi: 10.1002/mbo3.623

GONÇALVES, C., MARTINS, M., SOBRAL, P., COSTA, P.M., COSTA, M.H. (2019). An assessment of the ability to ingest and excrete microplastics by filter-feeders: A  case study with the Mediterranean mussel. Environmental Pollution 245, 600-606. (doi: 10.1016/j.envpol.2018.11.038)

RODRIGO, A.P.C., MARTINS, C., ALVES DE MATOS, A.P., COSTA, M.H. & COSTA, P.M. (2018). A morphoanatomical approach to the adaptive features of the epidermis and proboscis of a marine Polychaeta: Eulalia viridis (Phyllodocida: Phyllodocidae). Journal of Anatomy  233, 567-579. (doi: 10.1111/JOA.12870).

CUEVAS, N., MARTINS, M., RODRIGO, A.P., MARTINS, C. & COSTA, P.M. (2018). Explorations on the ecological role of toxin secretion and delivery in jawless predatory Polychaeta. Scientific Reports 8, 7635 (doi: 10.1038/s41598-018-26031-1)

CUEVAS, N., MARTINS, M. & COSTA, P.M. (2018). Risk assessment of pesticides in estuaries: A review addressing the persistence of an old problem in complex environments. Ecotoxicology 27, 1008–1018. (doi: 10.1007/s10646-018-1910-z)

MARTINS, M., SILVA, A., COSTA, M.H., MIGUEL, C. & COSTA, P.M. (2018). Co-exposure to environmental carcinogens in vivo triggers neoplasia-related hallmarks in low-genotoxicity events, even after removal of insult. Scientific Reports 8, 3649. (doi: 10.1038/s41598-018-21975-w)

BHATTACHARYA, K., SACCHETTI, C., COSTA, P.M., SOMMERTUNE, J., BRANDNER, B.D., MAGRINI, A., ROSATO, N., BOTTINI, N., BOTTINI, M. & FADEEL, B. (2018). Nitric oxide-dependent degradation of polyethylene glycol-modified single-walled carbon nanotubes: Implications for intra-articular delivery. Advanced Healthcare Materials, 7, 1700916. (doi: 10.1002/adhm.201700916)

GONÇALVES, C., MARTINS, M., COSTA, M.H., COSTA, P.M. (2018). Development of a method for the detection of polystyrene microplastics in paraffin-embedded histological sections. Histochemistry and Cell Biology 149, 187–191. (doi: 10.1007/s00418-017-1613-1)

LÍBALOVÁ, H., COSTA, P.M., OLSSON, M., FARCAL, L., ORTELLI, S., BLOSI, M., TOPINKA, J., COSTA, A.L. & FADEEL, B. (2018). Toxicity of surface-modified copper oxide nanoparticles in a mouse macrophage cell line: Interplay of particles, surface coating and particle dissolution. Chemosphere 196, 482–493. (doi: 10.1016/j.chemosphere.2017.12.182)

COSTA, P.M., GOSENS, I., WILLIAMS, A., FARCAL, L., PANTANO, D., BROWN, D.M., STONE, V., CASSEE, F.R., HALAPPANAVAR, S. & FADEEL, B. (2018). Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles. Journal of Applied Toxicology  38, 385–397. (doi: 10.1002/jat.3548)

BHATTACHARYA, K., KILIÇ, G., COSTA, P.M. & FADEEL, B. (2017). Cytotoxicity screening and cytokine profiling of nineteen nanomaterials enables hazard ranking and grouping based on inflammogenic potential. Nanotoxicology 11, 809–826. (doi: 10.1080/17435390.2017.1363309)

MADEIRA, D., ARAÚJO, J., VITORINO, R., COSTA, P.M., CAPELO, J.-L., VINAGRE, C. & DINIZ, M. (2017). Molecular plasticity under ocean warming: proteomics and fitness data provides clues for a better understanding of the thermal tolerance in fish. Frontiers in Physiology 8, 825. (doi: 10.3389/fphys.2017.00825)

CAEIRO, S., VAZ-FERNANDES, P., MARTINHO, A.P., COSTA, P.M., SILVA, M.J., LAVINHA, J., MATIAS-DIAS, C., MACHADO, A., CASTANHEIRA, I. & COSTA, M.H. (2017). Environmental risk assessment in a contaminated estuary: An integrated weight of evidence approach as a decision support tool. Ocean & Coastal Management 143, 51–62. (doi: 10.1016/j.ocecoaman.2016.09.026

RODRIGO, A.P. & COSTA, P.M. (2017). The role of the cephalopod digestive gland in the storage and detoxification of marine pollutants. Frontiers in Physiology. 8, 232. (doi: 10.3389/fphys.2017.00232)

FERNANDES, A.R., JESUS, J., MARTINS, P., FIGUEIREDO, S., ROSA, D., MARTINS, M.R.D.R.S., CORVO, M.L., CARVALHEIRO, M.C., COSTA, P.M., BAPTISTA, P.V. (2017). Multifunctional gold-nanoparticles: A nanovectorization tool for the targeted delivery of novel chemotherapeutic agents. Journal of Controlled Release 245, 52–61. (doi: 10.1016/j.jconrel.2016.11.021)