AQUATROPHYS is a capacity-building tool to promote excellence and innovation in marine science. The project will implement a Systems-Biology approach to unravel molecular networks underpinning phenotypic plasticity of commercial tropical marine fishes under global change scenarios. The main purpose is to create a permanent network of advanced training and expert exchange in experimental biology and marine multi-omics with access to state-of-the-art infrastructures. We will model fish nutritional and stress profiles under forecasted scenarios and relate them with life histories to identify actionable key events at the molecular scale and assess changes in fish stocks quality. By turning fundamental and applied research into knowledge-intensive training programs, the project will potentiate science output and expertise, altogether essential to develop climate-smart policies for sustainable fisheries and aquaculture in areas such as tropical seas that are particularly vulnerable.