Publications

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Journal Article
Branquinho, R., B. Veigas, J. V. Pinto, R. Martins, E. Fortunato, and P. V. Baptista. "Real-time monitoring of PCR amplification of proto-oncogene c-MYC using a Ta₂O₅ electrolyte-insulator-semiconductor sensor." Biosens Bioelectron 28 (2011): 44-9. AbstractWebsite

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Veigas, Bruno, Carla Portugal, Rita Valerio, Elvira Fortunato, Joao G. Crespo, and Pedro V. Baptista. "Scalable approach for the production of functional DNA based gold nanoprobes." Journal of Membrane Science 492 (2015): 528-535. Abstract

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Bernacka-Wojcik, Iwona, Hugo Aguas, Fabio Ferreira Carlos, Paulo Lopes, Pawel Jerzy Wojcik, Mafalda Nascimento Costa, Bruno Veigas, Rui Igreja, Elvira Fortunato, Pedro Viana Baptista, and Rodrigo Martins. "Single Nucleotide Polymorphism Detection Using Gold Nanoprobes and Bio-Microfluidic Platform With Embedded Micro lenses." Biotechnology and Bioengineering 112 (2015): 1210-1219. Abstract

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Daniela, Peixoto, Figueiredo Margarida, Malta Gabriela, Roma‐Rodrigues Catarina, Baptista Pedro V., Fernandes Alexandra R., Barroso Sónia, Carvalho Ana Luísa, Afonso Carlos A. M., Ferreira Luisa M., and Branco Paula S. "Synthesis, Cytotoxicity Evaluation in Human Cell Lines and in Vitro DNA Interaction of a Hetero‐Arylidene‐9(10H)‐Anthrone." European Journal of Organic ChemistryEuropean Journal of Organic Chemistry 2018 (2018): 545-549. AbstractWebsite

A new and never before reported hetero?arylidene?9(10H)?anthrone structure (4) was unexpectedly isolated on reaction of 1,2?dimethyl?3?ethylimidazolium iodide (2) and 9?anthracenecarboxaldehyde (3) under basic conditions. Its structure was unequivocally confirmed by X?ray crystallography. No cytotoxicity in human healthy fibroblasts and in two different cancer cell lines was observed, indicating its applicability in biological systems. Compound 4 interacts with CT?DNA by intercalation between the adjacent base pairs of DNA with a high binding affinity [Kb = 2.0?(±0.20)???105 m?1], which is 10?? higher than that described for doxorubicin [Kb = 3.2?(±0.23)???104 m?1]. Furthermore, compound 4 quenches the fluorescence emission of a GelRed?CT?DNA system with a quenching constant (KSV) of 3.3?(±0.3)???103 m?1 calculated by the Stern?Volmer equation.

Oliveira, B. B., B. Veigas, F. F. Carlos, A. Sánchez-Melsió, J. L. Balcázar, C. M. Borrego, and P. V. Baptista. "Water safety screening via multiplex LAMP-Au-nanoprobe integrated approach." Sci Total Environ 741 (2020): 140447. AbstractWebsite

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Report
Vinhas, Raquel, Alexandra Lourenço, Susana Santos, Marcos Lemos, Patrícia Ribeiro, Aida Botelho de Sousa, Pedro V. Baptista, and Alexandra R. Fernandes. A novel BCR-ABL1 mutation in a patient with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia. OncoTargets and Therapy, 2018.