Our publications

  1. Pereira, I. S., Pais. S. V., Borges, V., Borrego, M. J., Gomes, J. P., Mota, L. J. (2022). The type III secretion effector CteG mediates host cell lysis of Chlamydia trachomatis. Front Cell Infect Microbiol.
  2. Monteiro, I. P., Sousa, S., Borges, V., Gonçalves, P., Gomes, J. P., Mota, L. J., Franco, I. (2022). A search for novel Legionella pneumophila effector proteins reveals a strain specific nucleotropic effector. Front Cell Infect Microbiol. doi.org/10.3389/fcimb.2022.864626. 
  3. Bugalhão, J. N., Luís, M. P., Pereira, I. S., da Cunha, M., Mota, L. J. (2022). The Chlamydia trachomatis inclusion membrane protein CT006 associates with lipid droplets in eukaryotic cells. PLoS One. 17:e0264292. doi: 10.1371/journal.pone.0264292.   
  4. Bugalhão, J. N., Mota, L. J. (2019). The multiple functions of the numerous Chlamydia trachomatis secreted proteins: the tip of ghe iceberg. Microb Cell. 6: 414-449. doi: 10.15698/mic2019.09.691.
  5. Pais., S. V., Key, C. E., Borges, V., Pereira, I. S., Gomes, J. P., Fisher, D. J., Mota, L. J. (2019). CteG is a Chlamydia trachomatis effector protein that associates with the Golgi complex of infected host cells. Sci Rep. 9:6133. doi: 10.1038/s41598-019-42647-3
  6. Almeida, F., Luís, M. P., Pereira, I. S., Pais, S. V., Mota, L. J. (2018). The human centrosomal protein CCDC146 binds Chlamydia trachomatis inclusion membrane protein CT288 and is recruited to the periphery of the Chlamydia-containing vacuole. Front Cell Infect Microbiol. 8:254. doi:10.3389/fcimb.2018.00254.
  7. Franco, I. S., Pais, S. V., Charro, N., and Mota, L. J. (2017). Effector translocation assay: differential solubilization. In Methods in Molecular Biology: Bacterial Protein Secretion Systems, Methods and Protocols. In press - June 2017. Journet, L., Cascales, E. (Eds.). Humana Press, Springer Science+Business Media LLC. doi: 10.1007/978-1-4939-7033-9_35.  
  8. da Cunha, M., Pais, S. V., Bugalhão, J. N., Mota, L. J. (2017). The Chlamydia trachomatis type III secretion substrates CT142, CT143, and CT144 are secreted into the lumen of the inclusion. PLoS One. 12:e0178856. doi: 10.1371/journal.pone.0178856
  9. Inácio, Â. S, Nunes, A., Milho, C., Mota, L. J., Borrego, M. J., Gomes, J. P., Vaz, W. L., Vieira, O. V. (2016). In Vitro Activity of Quaternary Ammonium Surfactants against Streptococcal, Chlamydial, and Gonococcal Infective Agents. Antimicrob Agents Chemother. 60:3323-32. doi: 10.1128/AAC.00166-16.
  10. Domingues, L., Ismail, A., Charro, N., Rodríguez-Escudero, I., Holden, D. W., Molina, M., Cid, V. J., Mota, L. J. (2016) The Salmonella effector SteA binds phosphatidylinositol 4-phosphate for subcellular targeting within host cells. Cell Microbiol. 18:949-69. doi: 10.1111/cmi.12558.
  11. Bugalhão, J. N., Mota, L. J., Franco, I.S. (2016) Identification of regions within the Legionella pneumophila VipA effector protein involved in actin binding and polymerization and in interference with eukaryotic organelle trafficking. Microbiologyopen. 5:118-33. doi: 10.1002/mbo3.316.
  12. Bugalhão, J. N., Mota, L. J., and Franco, I. S. (2015). Bacterial nucleators: actin' on actin. Pathog Dis. 73. pii: ftv078. doi: 10.1093/femspd/ftv078
  13. Borges, V., Pinheiro, M., Antelo, M., Sampaio, D. A., Vieira, L., Ferreira, R., Nunes, A., Almeida, F., Mota, L. J., Borrego, M. J., and Gomes, J. P. (2015). Chlamydia trachomatis In Vivo to In Vitro Transition Reveals Mechanisms of Phase Variation and Down-Regulation of Virulence Factors. PLoS One. 10:e0133420. doi: 10.1371/journal.pone.0133420.
  14. Charro, N., and Mota, L. J. (2015). Approaches targeting the type III secretion system to prevent or treat bacterial infections. Expert Opinion On Drug Discovery. 10:373-87. doi: 10.1517/17460441.2015.1019860
  15. Domingues, L., Holden, D. W., and Mota, L. J. (2014). The Salmonella effector SteA contributes to the control of membrane dynamics of Salmonella-containing vacuoles. Infect. Immun. 82:2923-34. doi: 10.1128/IAI.01385-13.
  16. da Cunha, M., Milho, C., Almeida, F., Pais, S. V., Borges, V., Maurício, R., Borrego, M. J., Gomes, J. P., and Mota, L. J. (2014). Identification of type III secretion substrates of Chlamydia trachomatis using Yersinia enterocolitica as a heterologous system. BMC Microbiol. 14(1):40. doi: 10.1186/1471-2180-14-40.
  17. Pais, S. V., Milho, C., Almeida, F., Mota, L. J. (2013). Identification of novel type III secretion chaperone-substrate complexes of Chlamydia trachomatis. PLoS ONE. 8: e56292. doi: 10.1371/journal.pone.0056292.
  18. Almeida, F., Borges, V, Ferreira, R., Borrego, M. J., Gomes, J. P, and Mota, L. J. (2012). Polymorphisms in Inc proteins and differential expression of inc genes among Chlamydia trachomatis strains correlate with invasiveness and tropism of lymphogranuloma venereum isolates. J Bacteriol. 194: 6574-6785. doi: 10.1128/JB.01428-12
  19. McGourty, K. Thurston, T. L., Matthews, S.A., Pinaud, L., Mota, L. J., and Holden, D.W. (2012). Salmonella inhibits retrograde trafficking of mannose-6-phosphate receptors and lysosome function. Science. 338:963-967. doi: 10.1126/science.1227037
  20. Bacteria and protozoa differentially modulate the expression of Rab proteins (2012). Seixas, E., Ramalho, J. S., Mota, L. J., Barral, D. C, Seabra, M. C. (2012), PLoS ONE. 7:e39858. doi: 10.1371/journal.pone.0039858
  21. Schroeder N., Mota L. J., Méresse S. (2011). Salmonella-induced tubular networks. Trends Microbiol.19:268-277.  doi: 10.1016/j.tim.2011.01.006.