| Biomolecular Engineering Lab

A. Cecília Afonso Roque

Principal Investigator

Principal Investigator

Education

BSc in Chemical Engineering, IST-UTL, Portugal (1999)

PhD in Biotechnology, IST-UTL, Portugal (2004)

Habilitation in Bioengineering, FCT-UNL, Portugal (2015)

Professional Positions

Associate Professor with Habilitation at FCT/UNL (2017-present)
Assistant Professor at FCT/UNL (2005-2016)
Principal Investigator of Biomolecular Engineering Group (2005-present)
Post-Doctoral Researcher at INESC-MN and BERG, IST-UTL, Portugal (2005)
Post-Doctoral Researcher and Research Assistant at Institute of Biotechnology, University of Cambridge, UK (2004-2005)
Visiting Researcher at the Biomedical Engineering Department, Catholic University of America, Washington DC, USA (August 2004)

Previous Honors (between 2000-2005)

Young Investigators Award Hoffman-La Roche (2005)
Award CUF for PhD thesis (2004)
Visiting Fellowship Fundação Calouste Gulbenkian (2004)
AJ Banks Award Society of Chemical Industry (2004)
1K Business Plan Competition, Cambridge University Entrepeneurs Center (2000)

Previous publications (between 2004-2006)

Stevenson A.C., Araya-Kleinsteuber B., Kioupritzi E., Roque A.C.A., Lowe C.R.(2006), Noncontact excitation of quartz crystal resonator chips , Applied Physics Letters, 89: 083516.
Ruiu, L., Roque, A.C.A., Taipa, M.A., Lowe, C.R. (2006) De novo design, synthesis and screening of a combinatorial library of complementary ligands directed towards the surface of cutinase from Fusarium solani pisi , Journal of Molecular Recognition, 19: 372-378.
Araya-Kleinsteuber, B., Roque, A.C.A, Kioupritzi, E., Stevenson, A.C., and Lowe, C.R. (2006) Magnetic Acoustic Resonance Immunoassay (MARIA): a Multifrequency Acoustic Approach for the Non-labelled detection of Biomolecular Interactions , Journal of Molecular Recognition, 19: 379-385.
A.C. Stevenson, A.C.A. Roque, B. Araya-Kleinsteuber, E. Kioupritzi and C.R. Lowe (2006) Wireless excitation of quartz crystals immersed in an aqueous fluid , The Analyst, 131: 474-476.
Roque, A.C.A. and Lowe, C.R., (2006) Advances and applications of de novo designed affinity ligands in proteomics , Biotechnology Advances, 24: 17-26.
Roque, A.C.A. and Lowe, C.R. (2005) Lessons from nature: On the molecular recognition elements of the phosphoprotein binding-domains , Biotechology & Bioengineering, 91: 546-555.
Roque, A.C.A., Taipa, M.A., Lowe, C.R. (2005), Synthesis and screening of a rationally designed combinatorial library of affinity ligands mimicking protein L from Peptrostreptococcus magnus , Journal of Molecular Recognition, 18: 213-224.
Roque, A.C.A., Taipa, M.A., Lowe, C.R. (2005), An artificial Protein L for the purification of immunoglobulins and Fab fragments by affinity chromatography , Journal of Chromatography A, 1064: 157-167.
Roque, A.C.A., Lowe, C.R., Taipa, M.A. (2004), Antibodies and Genetically Engineered Related Molecules: Production and Purification , Biotechnology Progress, 20: 639-654.
Roque, A.C.A., Taipa, M.A., Lowe, C.R. (2004), A new method for the screening of solid phase combinatorial libraries for affinity chromatography , Journal of Molecular Recognition, 17:262-267.