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Doxorubicin-sensitive and -resistant colorectal cancer spheroid models: assessing tumor microenvironment features for therapeutic modulation

We developed three-dimensional cancer models that mimic the interactions in the TME and the tumor structure and complexity is of great relevance to cancer research and drug development.

Shrinking Cancer Research Barriers: Crafting Accessible Tumor-on-Chip

A simple method for developing ToC devices in under 10 minutes, using thermo-sensitive polystyrene sheets – “Shrinky-dinks”. The process only involves pattern engraving, layer bonding, and heat shrink to the final size.

Mild hyperthermia via gold nanoparticles and visible light irradiation for enhanced siRNA and ASO delivery in 2D and 3D tumour spheroids

Novel transfection approach for gene therapy applications in 2D and 3D tumor models based on the use of mild photothermy mediated by AuNPs combined with visible laser irradiation that might pave the way for the spatial-temporal control of gene modulation - PAPER

Membrane-localized magnetic hyperthermia promotes intracellular delivery

We use membrane-localized magnetic hyperthermia to promote the internalization of cell-impermeant probes.

Nanoparticles for gene silecinging in 2D cell culture vs. 3D tumor spheroid

Transitioning from 2D to 3D models demands an understanding of altered internalization mechanisms and microenvironmental influences.

ARMS-HRMA for KRAS mutation detection in clinical samples

Liquid biopsies, and particularly the analysis of circulating tumor DNA, are emerging as an interesting means for diagnosis, prognosis, and predictive biomarker discovery.

Inaugural session - Academic year 2024/2025

27 January 2025

Presentation <slides>

Save the Date - European Plant Phenomics Symposium 2025

We warmly welcome you to the European Plant Phenomics Symposium (EPPS), bringing together scientists from academia and industry as well as stakeholders dedicated to advancing plant phenotyping research and technology in Europe.

This symposium provides a collaborative and interactive platform for sharing the latest innovations, methods, and applications in phenotyping with the goal to address the pressing challenges of sustainable agriculture, climate resilience, and food security across Europe and beyond.

The EPPS will take place:

Congratulations to Tomás M. Fernandes for finishing his PhD in Biotechnology!

Tomás M. Fernandes successfully defended his PhD on December 17th.

Congratulations to our new MSc's!

Today, Mafalda Fernandes and Alexandre Almeida defended their Master Thesis in Biochemistry!

Nota de pesar

É com profunda tristeza que a FACIT recebeu a notícia do falecimento do Querido Dr. Gaspar. O Dr. Gaspar era sócio e  membro da comissão  fiscal da FACIT.Gratidão pela sua colaboração.

Que a sua alma descanse em Paz.
 
Direção da FACIT

Congratulations to Pilar C. Portela for finishing her PhD in Biotechnology!

On December 9th, Pilar C. Portela defended her PhD Thesis entitled "Cytochromes in Geobacter: fostering sustainable sources of energy production" with great success!

Training in Plant Phenotyping Data Standards

Hybrid Workshop on Data Standards in Plant Phenotyping – 26, 27 & 28 February 2025

https://www.nordplant.org/2024/11/26/hybrid-workshop-on-data-standards-in-plant-phenotyping-26-27-28-february-2025/

Registration deadline 31 January 2025.