Project funded to develop a new generation of enzymes for immunomodulation in cancer therapy
July 28, 2021
Ana Luísa Carvalho, Angelina Palma, Maria João Romão and Eurico Cabrita, researchers from UCIBIO at FCT NOVA, integrate the consortium of the “GlycoMed - A new generation of enzymes for biofilm dispersion and immunomodulation in cancer” project that aims to develop a catalog of carbohydrate active enzyme with biomedical applications (GlycoZymes). The project has been awarded a 435 K€ project grant, funded by the Regional Operational Programme – Portugal 2020, and the consortium includes also the company NZYTech, Lda and the Faculty of Veterinary Medicine-ULisboa.
“More specifically, a collection of enzymes capable of digesting the main exopolissacharides present in biofilms produced by the pathogenic bacteria Pseudomonas aeruginosa (Pel, Psl and alginate) and Staphilococcus aureus (PNAG) will be developed in order to promote its dispersion, allowing a better penetration of antimicrobial agents used in the treatment of chronic infections”, explain the UCIBIO researchers involved in the project.