Dear Participants,

It is with great pleasure that we welcome you to this specialized course on functionalized main-group organometallics in organic synthesis, led by Prof. Dr. Paul Knochel, a leading expert in the field of organometallic chemistry. Prof. Dr. Paul Knochel is internationally recognized for his groundbreaking research in the development of highly functionalized organometallic reagents and their application in complex organic synthesis. His innovative work has significantly advanced the fields of stereoselective synthesis, C-H activation, and metal-catalyzed reactions, making him one of the foremost experts in organometallic chemistry.

Participating in this course will provide you with the unique opportunity to learn directly from Prof. Knochel, gaining invaluable insights into the latest methodologies and real-world applications that are shaping the future of organic synthesis.

Throughout this course, Prof Knochel will explore the critical preparation methods of Li, Na, Mg, and Zn organometallics, with a particular focus on their functionalization and applications in organic synthesis. Starting with the oxidative addition of metals to organic halides and progressing through topics like stereoselective synthesis, transmetalation reactions, and C-H activation, you will gain valuable insights into some of the most important reactions in modern chemistry. Additionally, Prof Knochel will cover key industrial techniques such as continuous flow reactions, as well as cutting-edge hydro- and carbo-metalation strategies and transition metal-catalyzed cross-couplings.

Prof. Knochel’s expertise will guide you through these advanced topics, providing you with an unparalleled understanding of how these methods are applied in natural product synthesis, pharmaceutical development, and material science. We are thrilled to have you join us for this transformative experience and look forward to the innovative discussions and hands-on learning that lie ahead.

Best regards,

Maria Manuel Marques