Biomaterials
Semester:
Fall
Offered:
2014 Materials for medical applications can be natural or of synthetic origin, but in all cases are designed to interact with the human body. The Biomaterials course will be structured in two parts.
- In part one, we will analyze the structure and behavior of synthetic materials used as implants to treat injuries and diseases: metals, polymers, ceramics and glasses, composite materials (here we include cellular materials).
- Part two will focus on the structure and properties of natural biological tissues, including hard and soft tissues and tissue inflammatory response. In this part of the course we will examine the interface between biological and synthetic materials, critical in establishing and maintaining biocompatibility.
Objectives
To acquire deep knwoledge in the area of biomaterials with detailed understanding of the composition and propertis of the major classes of biomaterial used in medical devices, manufacture process and applications, intereactions with implanted biomaterials, and issues associated with the use of surface modification methods to ehnahce the biocompatibility of materials. Regulatory and standards associated with quality will be included
Lectures
- Introduction: Economical, Ethic and Social issues in Biomaterials Science
- Synthetic biomaterials: structure-property relashionships
- Protein-biomaterial interactions
- Blood-biomaterial interactions.
- Immune response to biomaterials
- Wound healing process
- Biomimetic and intelligent materials
- Biocompatibility evaluation
Lab classes
- L1 - Synthesis and Characterization of hydroxyapatite powders by sol-gel
- L2 - Synthesis of magnetite nanoparticles and thermal characterization for hyperthermia applications
- L3 - Controlled release of encapsulated BSA from polycaprolactone microspheres
- L4 - Production and characterization of fibres obtained by electrospinning and rotary-jet spinning
- L5 - Preparation and characterization of 3D porous scaffolds by particle-agragation and centrifugation