Publications

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2021
Aggarwal, SD, Lloyd* AJ, Yerneni SS, Narciso AR, Shepherd J, Roper DI, Dowson C, Filipe* SR, Hiller* NL.  2021.  A Molecular Link between Cell Wall Biosynthesis, Translation Fidelity, and Stringent Response in Streptococcus pneumoniae. Proc. Natl. Acad. Sci. USA. 118(14):e2018089118.
2019
Vaz, F, Kounatidis I, Covas G, Parton RM, Harkiolaki M, Davis I, Filipe* SR, Ligoxygakis* P.  2019.  Accessibility to peptidoglycan is important for recognition of Gram-positive bacteria in Drosophila. Cell Reports. 27(8):2480-2492.
2015
Reed, P, Atilano ML, Alves R, Hoiczyk E, Sher X, Reichmann NT, Pereira PM, Roemer T, Filipe SR, Pereira-Leal JB, Ligoxygakis P, Pinho MG.  2015.  Staphylococcus aureus survives with a minimal peptidoglycan synthesis machinery but sacrifices virulence and antibiotic resistance. PLoS Pathogens. 11:e1004891.
2014
Atilano, ML, Pereira PM, Vaz F, Catalão MJ, Reed P, Grilo IR, Sobral RG, Ligoxygakis P, Pinho MG, Filipe SR.  2014.  Bacterial autolysins trim cell surface peptidoglycan to prevent detection by the Drosophila innate immune system. eLife. 3:e02277.
2011
Atilano, ML, Yates J, Glittenberg M, Filipe* SR, Ligoxygakis* P.  2011.  Wall teichoic acids of Staphylococcus aureus limit recognition by the Drosophila Peptidoglycan Recognition Protein-SA to promote pathogenicity. PLoS Pathogens. 7:e1002421.
2008
Wang, L, Gilbert RJC, Atilano ML, Filipe SR, Gay NJ, Ligoxygakis P.  2008.  Peptidoglycan Recognition Protein-SD provides versatility of receptor formation in Drosophila immunity. Proc. Natl. Acad. Sci. USA. 105:11881-11886.
2006
Wang, L, Weber AN, Atilano ML, Filipe SR, Gay NJ, Ligoxygakis P.  2006.  Sensing of Gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA. EMBO J. 25:5005-5014.
2005
Filipe, SR, Tomasz A, Ligoxygakis P.  2005.  Requirements of peptidoglycan structure allowing detection by the Drosophila Toll pathway. EMBO Reports. 6:327-333.
2004
Sherratt, DJ, Soballe B, Barre F-X, Filipe SR, Massey T, Lau I, Yates J.  2004.  Recombination and chromosome segregation. Phil. Trans. R. Soc. Lond. B. 359:61-69.
Gardete, S, Ludovice AM, Sobral RG, Filipe SR, de Lencastre H, Tomasz A.  2004.  The role of murE in the expression of b-lactam antibiotic resistance in Staphylococcus aureus. J. Bacteriol. 186:1705-1713.
2003
Lau, IF, Filipe SR, Soballe B, Okstad O-A, Barre F-X, Sherratt DJ.  2003.  Spatial and temporal organization of replicating Escherichia coli chromosomes. Mol Microbiol. 49:731-743.
2001
1999
de Lencastre, H, Wu SW, Pinho MG, Ludovice AM, Filipe S, Gardete S, Sobral R, Gill S, Chung M, Tomasz A.  1999.  Antibiotic resistance as a stress response: complete sequencing of a large number of chromosomal loci in Staphylococcus aureus strain COL that impact on the expression of resistance to methicillin. Microb. Drug Resist. 5:163-175.