Potentiating angiogenesis arrest in vivo via laser irradiation of peptide functionalised gold nanoparticles
- Citation:
- Pedrosa, P, Heuer-Jungemann A, Kanaras AG, Fernandes AR, Baptista PV. 2017. Potentiating angiogenesis arrest in vivo via laser irradiation of peptide functionalised gold nanoparticles, 2017. 15(1):85.
Abstract:
Anti-angiogenic therapy has great potential for cancer therapy with several FDA approved formulations but there are considerable side effects upon the normal blood vessels that decrease the potential application of such therapeutics. Chicken chorioallantoic membrane (CAM) has been used as a model to study angiogenesis in vivo. Using a CAM model, it had been previously shown that spherical gold nanoparticles functionalised with an anti-angiogenic peptide can humper neo-angiogenesis.
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