Publications

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2021
Martins, CF, Neves LA, Chagas R, Ferreira LM, Afonso CAM, Coelhoso IM, Crespo JG, Mota PBJ.  2021.  Modelling CO2 absorption in aqueous solutions of cholinium lysinate ionic liquid, OCT 1. CHEMICAL ENGINEERING JOURNAL. 421, Number 2 Abstract
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Martins, CF, Neves LA, Chagas R, Ferreira LM, Coelhoso IM, Crespo JG.  2021.  Removing CO2 from Xenon anaesthesia circuits using an amino-acid ionic liquid solution in a membrane contactor, NOV 15. SEPARATION AND PURIFICATION TECHNOLOGY. 275 Abstract
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2020
Martins, CF, Neves LA, Chagas R, Ferreira LM, Afonso CAM, Crespo JG, Coelhoso IM.  2020.  CO2 removal from anaesthesia circuits using gas-ionic liquid membrane contactors, NOV 1. SEPARATION AND PURIFICATION TECHNOLOGY. 250 Abstract
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2018
Martins, S, Avo J, Lima J, Nogueira J, Andrade L, Mendes A, Pereira A, Branco PS.  2018.  Styryl and phenylethynyl based coumarin chromophores for dye sensitized solar cells, FEB 15. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY. 353:564-569. Abstract
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2013
Vilas-Boasa, V, Silva R, Nunes C, Reis S, Ferreira L, Vieira C, Carvalho F, de Bastos ML, Remiao F.  2013.  Mechanisms of P-gp inhibition and effects on membrane fluidity of a new rifampicin derivative, 1,8-dibenzoyl-rifampicin, JUL 18. TOXICOLOGY LETTERS. 220:259-266., Number 3 Abstract

Purpose: To assess P-glycoprotein (P-gp)-modulation ability and the mechanisms of P-gp inhibition mediated by a new synthetic rifampicin derivative, 1,8-dibenzoyl-rifampicin (DiBenzRif), in an in vitro model of the blood-brain barrier (BBB), RBE4 cells, and in membrane mimetic models (liposomes). Methods: P-gp expression (western blot) and activity {[}rhodamine 123 accumulation studies] were assessed until 72 h of exposure to DiBenzRif. The effects on intracellular ATP levels and on P-gp ATPase activity were studied using luciferin-luciferase bioluminescence assay. Membrane fluidity changes were tracked by steady-state anisotropy measurements. Non-P-gp-related rhodamine 123 accumulation was evaluated using liposomes prepared with the main lipids present in RBE4 cell membranes. Results: A significant increase in intracellular rhodamine 123 content was observed in DiBenzRif-treated cells at all tested time-points. This effect was associated with a significant reduction in ATP intracellular levels, the inhibition of P-gp ATPase activity and a significant increase in membrane fluidity. DiBenzRif also favoured rhodamine 123 accumulation in a liposomal model of RBE4 cells, suggesting that it may be useful in increasing intracellular levels of substances that passively diffuse into the cells. Conclusion: DiBenzRif-induced inhibitory effect on P-gp increases xenobiotic accumulation in BBB cells, which may contribute to the development of therapeutic adjuvants to enhance brain penetration of drugs. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

Ferreira, PS, Nogueira TB, Costa VM, Branco PS, Ferreira LM, Fernandes E, Bastos ML, Meisel A, Carvalho F, Capela JP.  2013.  Neurotoxicity of ``ecstasy{''} and its metabolites in human dopaminergic differentiated SH-SY5Y cells, FEB 4. TOXICOLOGY LETTERS. 216:159-170., Number 2-3 Abstract
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Gawande, MB, Branco PS, Nogueira ID, Ghumman ACA, Bundaleski N, Santos A, Teodoro OMND, Luque R.  2013.  Catalytic applications of a versatile magnetically separable Fe-Mo (Nanocat-Fe-Mo) nanocatalyst. GREEN CHEMISTRY. 15:682-689., Number 3 Abstract
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Gawande, MB, Bonifacio VDB, Varma RS, Nogueira ID, Bundaleski N, Ghumman ACA, Teodoro OMND, Branco PS.  2013.  Magnetically recyclable magnetite-ceria (Nanocat-Fe-Ce) nanocatalyst - applications in multicomponent reactions under benign conditions. GREEN CHEMISTRY. 15:1226-1231., Number 5 Abstract
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Gawande, MB, Rathi AK, Branco PS, Potewar TM, Velhinho A, Nogueira ID, Tolstogouzov A, Ghumman ACA, Teodoro OMND.  2013.  Nano-MgO-ZrO2 mixed metal oxides: characterization by SIMS and application in the reduction of carbonyl compounds and in multicomponent reactions. RSC ADVANCES. 3:3611-3617., Number 11 Abstract
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2012
Gawande, MB, Rathi A, Nogueira ID, Ghumman CAA, Bundaleski N, Teodoro OMND, Branco PS.  2012.  A Recyclable Ferrite-Co Magnetic Nanocatalyst for the Oxidation of Alcohols to Carbonyl Compounds, OCT. CHEMPLUSCHEM. 77:865-871., Number 10 Abstract
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Gawande, MB, Rathi AK, Branco PS, Nogueira ID, Velhinho A, Shrikhande JJ, Indulkar UU, Jayaram RV, Ghumman ACA, Bundaleski N, Teodoro OMND.  2012.  Regio- and Chemoselective Reduction of Nitroarenes and Carbonyl Compounds over Recyclable Magnetic Ferrite-Nickel Nanoparticles (Fe3O4-Ni) by Using Glycerol as a Hydrogen Source, OCT. CHEMISTRY-A EUROPEAN JOURNAL. 18:12628-12632., Number 40 Abstract
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Gawande, MB, Velhinho A, Nogueira ID, Ghumman CAA, Teodoro OMND, Branco PS.  2012.  A facile synthesis of cysteine-ferrite magnetic nanoparticles for application in multicomponent reactions-a sustainable protocol. RSC ADVANCES. 2:6144-6149., Number 15 Abstract
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2007
Antunes, AMM, Bonifacio VDB, Nascimento SCC, Lobo AM, Branco PS, Prabhakar S.  2007.  Palladium(II) mediated aziridination of olefins with bromamine-T as the nitrogen source: scope and mechanism, JUL 23. TETRAHEDRON. 63:7009-7017., Number 30 Abstract
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2005
Tan, C, de Noronha RG, Roecker AJ, Pyrzynska B, Khwaja F, Zhang ZB, Zhang HC, Teng Q, Nicholson AC, Giannakakou P, Zhou W, Olson JJ, Pereira MM, Nicolaou KN, Van Meir EG.  2005.  Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway, JAN 15. CANCER RESEARCH. 65:605-612., Number 2 Abstract
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