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2017
Lourenço, SC, Torres CAV, Nunes D, Duarte P, Freitas F, Reis MAM, Fortunato E, Moldão-Martins M, da Costa LB, Alves VD.  2017.  Using a bacterial fucose-rich polysaccharide as encapsulation material of bioactive compounds. International Journal of Biological Macromolecules. 104:1099-1106. AbstractWebsite

The potential of a bacterial exopolysaccharide named FucoPol, produced by the bacterium Enterobacter A47, as encapsulation matrix was explored. Spherical capsules with a smooth surface were produced by spray drying. The obtained microcapsules had average diameters ranging from 0.5 to 26.7μm and presented thin walls (thickness from 222 to 1094nm). The capsules were loaded with two bioactive compounds: gallic acid (GA) and oregano essential oil (OEO). Both bioactive materials were encapsulated in FucoPol particles, retaining their antioxidant activity after the drying process. Release studies showed that GA release in simulated gastric and intestinal fluids was faster than that of OEO, envisaging that the latter had established stronger interactions with the polymer matrix. These results suggest that FucoPol has a good potential for use as encapsulating material of bioactive compounds for application in several areas, including food, cosmetic or pharmaceutical products.