@article {Batalha2016, title = {Phosphopeptide Enrichment Using Various Magnetic Nanocomposites: An Overview}, journal = {Phospho-Proteomics}, volume = {1355}, year = {2016}, note = {

n/a

}, pages = {193{\textendash}209}, abstract = {

Magnetic nanocomposites are hybrid structures consisting of an iron oxide (Fe3O4 /$\gamma$-Fe2O3 ) superparamagnetic core and a coating shell which presents affi nity for a specifi c target molecule. Within the scope of phosphopeptide enrichment, the magnetic core is usually fi rst functionalized with an intermediate layer of silica or carbon to improve dispersibility and increase specifi c area, and then with an outer layer of a phosphate-affi nity material. Fe3O4 -coating materials include metal oxides, rare earth metal-based compounds, immobilized-metal ions, polymers, and many others. This chapter provides a generic overview of the different materials that can be found in literature and their advantages and drawbacks.

}, keywords = {Affinity, Hybrid materials, Magnetic nanocomposites, Phosphopeptide enrichment}, isbn = {978-1-4939-3048-7}, doi = {10.1007/978-1-4939-3049-4}, url = {http://link.springer.com/10.1007/978-1-4939-3049-4}, author = {Batalha, {\'I}ris L. and Roque, Ana Cec{\'\i}lia A} }