<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Faria, Jaime</style></author><author><style face="normal" font="default" size="100%">Bruno Dionísio</style></author><author><style face="normal" font="default" size="100%">Iris Soares</style></author><author><style face="normal" font="default" size="100%">Baptista, Ana Catarina</style></author><author><style face="normal" font="default" size="100%">Ana Cláudia Marques</style></author><author><style face="normal" font="default" size="100%">Lídia Gonçalves</style></author><author><style face="normal" font="default" size="100%">Ana Bettencourt</style></author><author><style face="normal" font="default" size="100%">Carlos Baleizão</style></author><author><style face="normal" font="default" size="100%">Ferreira, Isabel</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Cellulose acetate fibres loaded with daptomycin for metal implant coatings</style></title><secondary-title><style face="normal" font="default" size="100%">Carbohydrate polymers</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2021</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://doi.org/10.1016/j.carbpol.2021.118733</style></url></web-urls></urls><pages><style face="normal" font="default" size="100%">118733</style></pages><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Multifunctional polymeric coatings containing drug delivery vehicles can play a key role in preventing/reducing biofilm formation on implant surfaces. Their requirements are biocompatibility, good adhesion, and controllable drug release. Although cellulose acetate (CA) films and membranes are widely studied for scaffolding, their applications as a protective coating and drug delivery vehicle for metal implants are scarce. The reason is that adhesion to stainless steel (SS) substrates is non-trivial. Grinding SS substrates enhances the adhesion of dip-coated CA films while the adhesion of electrospun CA membranes is improved by an electrosprayed chitosan intermediate layer. PMMA microcapsules containing daptomycin have been successfully incorporated into CA films and fibres. The released drug concentration of 3 x10-3 mg/mL after 120 minutes was confirmed from the peak luminescence intensity under UV radiation of simulated body fluid (SBF) after immersion of the fibres.&lt;/p&gt;
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