@article {2308,
	title = {Sub-cellular partitioning of Zn, Cu, Cd and Pb in the digestive gland of native Octopus vulgaris exposed to different metal concentrations (Portugal)},
	journal = {Science of the Total Environment},
	volume = {390},
	number = {2-3},
	year = {2008},
	note = {<p>Times Cited: 6</p>
},
	month = {Feb 15},
	pages = {410-416},
	abstract = {<p>Cd and Pb and their sub-cellular distributions were determined in Cu Concentrations of Zn,, composite samples of digestive glands of the common octopus, Octopus vulgaris caught from two areas of the Portuguese coast characterised by contrasting metal contamination. Minor contents of Zn (1\%), Cu (2\%), Cd (6\%) and Pb (7\%) were found in the insoluble fraction, consisting of nuclei, mitochondria, lysosomes and microsome operationally separated from the whole digestive gland through a sequential centrifugation. A tendency for linear relationships between metal concentrations in nuclei, mitochondria, lysosomes and whole digestive gland was observed. These relationships suggest that despite low metal content organelles responded to the increasing accumulated metals, which means that detoxifying mechanism in cytosol was incomplete. Poorer correlations between microsome and whole digestive gland did not point to metal toxicity in the analysed compartments. However, the high accumulated Cd indicated that O. vulgaris is an important vehicle of this element to its predators in the coastal environment. (c) 2007 Elsevier B.V. All rights reserved.</p>
},
	isbn = {0048-9697},
	url = {http://dx.doi.org/10.1016/j.scitotenv.2007.10.029},
	author = {Raimundo, J. and Vale, C. and Duarte, R. and Moura, I.}
}
