Jacopo Marangon

PhD Student, FCT-UNL
Email: j.marangon(at)campus.fct.unl.pt
Tel: + 351 21 294 83 00, ext. 10937

PhD Thesis
Study of molybdo-enzymes involved in the reduction of nitrate and nitrite
Supervisor: José J.G. Moura
Co-supervisor: Pablo Gonzalez, Luisa Maia

Research Activities - Keywords
• Bioinorganic Chemistry, Biophysics, Biocatalysis
• Bacterial systems: denitrifiers and sulphate reducers
• Membrane proteins purification
• Molybdo-enzymes structure-function relationships
• Nitrate reductases (membrane and periplasmic), aldehyde oxidoreductase
• Spectroscopy (NMR and EPR)
• Bio-electrochemistry (Protein Film Voltammetry)
• Enzyme kinetic
• Protein crystallography

Selected References
Kinetic, structural, and EPR studies reveal that aldehyde oxidoreductase from Desulfovibrio gigas does not need a sulfido ligand for catalysis and give evidence for a direct Mo-C interaction in a biological system
Santos-Silva T, Ferroni F, Thapper A, Marangon J, Gonzalez PJ, Rizzi AC, Moura I, Moura JJG, Romao MJ, Brondino CD
J Am Chem Soc (2009) 131:7990-7998

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