Available Technologies

Circular Dichroism

Circular Dichroism

Circular Dichroism (CD) is an absorption spectroscopy method based on the differential absorption of left and right circularly polarized light. CD spectroscopy can provide information on the structure of proteins, peptides, nucleic acids and other chiral compounds having a wide range of applications in many different fields.

Application examples:

Proteins

Confocal Microscopy

Confocal Microscopy

Confocal microscopy is a fluorescence optical imaging technique for increasing optical resolution and contrast of a micrograph. This technique uses a laser point source to scan the sample and a pinhole to reduce collection of light from outside the focal plane and allows investigators to acquire thin optical sections at various focal planes. Stacks of images can be acquired for 3D visualization.

Differential Scanning Calorimetry

Differential Scanning Calorimetry

Differential Scanning Calorimetry (DSC) is a thermoanalytical technique that measures the heat absorbed or released by a sample as it is heated or cooled. DSC is widely used for the thermodynamic analysis of biomolecules and nanoparticles.

Application examples:

Flow Cytometry

Flow Cytometry

Flow cytometry is a technology that simultaneously measures and then analyses multiple physical characteristics of single particles as they flow in a fluid stream through a beam of light.

Application examples:

Isothermal Titration Calorimetry

Isothermal Titration Calorimetry

Isothermal titration calorimetry (ITC) characterizes the thermodynamic driving forces of critical molecular interactions and defines molecular stabilities, being an essential tool in the design of effective biomedical and pharmaceutical treatments. This analysis is based on the accurate measurement of the rate of heat absorbed or evolved when the biomolecule of interest interacts specifically or non-specifically with another macromolecule or ligand.

MicroScale Thermophoresis

MicroScale Thermophoresis

MicroScale Thermophoresis (MST) is based on the directed movement of molecules in a temperature gradient which strongly depends on a variety of molecular properties such as size, charge, hydratation shell or conformation thus being a powerfull technique to quantify biomolecular interactions.

Application examples:

Multi Parametric Surface Plasmon Resonance

Multi Parametric Surface Plasmon Resonance

Traditional surface plasmon resonance is an optical technique established as a powerful method to monitor label-free biomolecular interactions in liquids.